Thin readers fit in a Vive Pro 2, but thick ones are a problem. I don't know about other HMD's compatibility with glasses. Custom lenses can be bought and installed in HMDs. You don't need 2 eyes, but you'll still need the GPU to meet the demands of conventional 2-eyed VR;
https://www.reddit.com/r/virtualreality/comments/r81vvz/can_i_render_only_one_eye_in_vr/

Yes. Get some prescription lens inserts for your vr headset and no need to wear glasses as well